Endocrine Abstracts

BackgroundLeptin is suggested to be a permissive factor for puberty by stimulating the secretion of gonadotrophin-releasing hormone by the hypothalamic neurons, and luteinising and follicle-stimulating hormones by pituitary cells.ObjectiveTo document the ultrastructural changes that occur in the ovarian follicles of immature albino rats treated with leptin when compared with controls.Su...

BackgroundLeptin serves as a signal to the central nervous system with information on the critical amount of adipose tissue stores that is necessary for activation of the hypothalamic-pituitary-ovarian axis.ObjectivesTo determine the endometrial histological changes and vaginal cytological alterations, suggestive of ovulation and the onset of the oestrus phase of the oestrus cycle, that occur in the immature ...